September in Santa Cruz del Quiché is the cloudiest month of the year. In September, the weather in Santa Cruz del Quiché is typically warm. Average daily high temperature in September is about 22 degrees above zero. On average, Santa Cruz del Quiché has 28 rainy and 2 cloudy days in September. The rains are usually heavy. September as well as May, June, July, and August is considered the most uncomfortable time to visit Santa Cruz del Quiché.