In October, the weather in Cuiabá is typically hot. Average daily high temperature in October is about 33 degrees above zero. On average, Cuiabá has 15 rainy, 12 cloudy, 3 sunny, and 1 partly cloudy day in October. The rains are usually heavy. October as well as January, February, March, and April is considered the most uncomfortable time to visit Cuiabá.